Endocrine Abstracts

Introduction: Riedel’s thyroiditis, also known as invasive fibrous thyroiditis, is a rare disorder of unknown etiology in which characterized by invasive fibrosis that partially destroys the thyroid gland and extends into adjacent neck structures. The diagnosis of Riedel’s thyroiditis is clinically difficult because this form of thyroiditis can mimic lymphoma or Hashimoto’s thyroiditis during preoperative radiologic, and pathologic examination. Sonographic featu...

The most common reason for the rare condition of hyperinsulinemia-related hypoglycaemia is insulinoma, a tumor of pancreatic islet cells. However, nesidioblastosis characterized by diffuse or focal hyperplasia of the pancreatic islet cells is the most common cause of hyperinsulinemic hypoglycemia in newborns. Nesidioblastosis seen in newborns is now called ‘persistent hyperinsulinemic hypoglycemia of infancy’ (PHHI) while the condition in adults is called ‘nonin...

Dopamine agonists are the treatment of choice for prolactinomas and surgery is warranted only when the response to medical therapy is poor, not tolerated, or in those with compromised vision or with extensive invasion. We describe the two cases of a giant prolactinoma treated with cabergoline alone and next to surgery and gamma-knife.Case 1: A 30-year-old man admitted with headache and visual defect, cranial magnetic resonance imaging (MRI) revealed a in...

Case: A 75-year-old male patient was treated for lung adenocarcinoma 12 years ago. During the routine imaging studies of the patient who was followed without treatment after curing, a suspicious, non-adenomatous lesion in the right adrenal gland, 16×9 mm in size was detected by thoracic computed tomography. Serum aldosterone/renin ratio and urine catecholamine tests were normal with no complaints of suspicion for pheochromocytoma. F18FDG PET-CT showed an increase in metab...

A 60-year-old male patient who presented with left hip and knee pain was found to be compatible with primary hyperparathyroidism (PTH:2233 pg/ml, calcium: 15.7 mg/dl, phosphorus: 2.9 mg/dl creatinin:1.99 mg/dl, 25-OH-D:9.7 μg/l, ALP:532 mU/ml). Bone grafts of the patient showed multiple lytic lesions in the pelvis, cranium and long-bones. Neck ultrasonography showed hypoechoic solid nodule with cystic areas, 2×2 cm with size in the left thyroid gland inferior region ...

Introduction: Hyalinizing trabecular adenomas (HTA) of the thyroid gland is a rare neoplasm of follicular cell origin. HTA can be present as a thyroid nodule or incidental finding in a thyroidectomy specimen. HTA is generally accepted to be a benign tumor, but their cytological features can be similar to those of papillary thyroid carcinoma (PTC).Case report: A 59 year old woman, who had cholangiocellular carcinoma, admitted to our institution with a sol...

Aim: Delayed gastric emptying affects a substantial proportion of patients with long-standing diabetes. On the other hand changes in gastric incretin hormones also play an important role in the pathophysiology of diabetes. In our study, we aimed to investigate the incidence of gastrointestinal disease in patients with newly diagnosed diabetes and pre-diabetes.Methods: A total of 73 patients with newly diagnosed pre-diabetes and diabetes were included in ...

Aim: Metformin is usually well-tolerated and commonly used oral-antidiabetic in type-2 diabetes and pre-diabetes. The most common side effects are gastrointestinal (GI) ones. It is proposed that, extended-release form of metformin has less gastrointestinal side effects. We aimed to compare the extended-release and normal-release form metformin in type-2 diabetic and prediabetic patients for gastrointestinal tolerability, weight effect and glycemic control.<p class="abstext...

Introduction: SGLT2 inhibitors have been an important step in the treatment of diabetes. With numerous controlled experimental studies of these antidiabetic drugs, evaluation of real-life data after entry into clinical practice is an important condition. In our study, it was aimed to evaluate short-term results on glycemic control and weight loss in a narrow group of patients in the single tertiary medical center.Methods: The study was retrospectively de...

Introduction: Polycystic ovary syndrome (PCOS) is a common, multifaceted endocrinopathy associated with metabolic alterations such as insulin resistance, hyperinsulinemia, dyslipidemia, and obesity, and thereby an increased risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Endothelial dysfunction and chronic inflammation are early findings in the atherosclerotic process. Elevated serum levels of uric acid may reflect low-grade chronic inflamm...